If you found this site useful, please cite: Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

Brazil-nut Protein: Ber e 2 | 11S Globulin Seed Storage Protein

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 465 amino acids

MAKLFLLSLGIFLLFHCCLAIEYEQEELYECRIQRLTAQEPQYRLEAEAGVSEVWDYTDQQFRCAGVAALRNTIRPQGLLLPVYTNAPKLYYVTQGRGILGVLMPGCPETFQSMSQFQGSREQEEERGRFQDQHQKVHHLKKGDIIAIPAGVALWCYNDGDEDLVTVLVQHTASDLNQLDQNPRHFFLAGNIQRSQKQRGERYGLRGGQQILADNVFKGFNMEALADVLGFGMDTETARKVRGEDDQRGHIVRVEQGLKVIRPPRIREELEQQEGGGYNGLEETICSATFIQNIDNPAEADFYNPRAGRLTTVNSLKVPILTFLQLSAMKGVLYENAMMAPLWRLNANSVVYAVRGEARVQIVDHRGETVFDDNLREGQMVVVPQNFVVVKQAGSRGFEWVVFNTNDNALFSTAAGRTSPLRGIPVGVLANAYRLSQEEARRIKLNRDEAVLFQPGSRSRGRASA

UniProt: Q84ND2   IUIS: Ber e 2

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1Peptide2Exp.3ESP4CONSeQ5
R LEAEAGVSEVWDYTDQQFR C 0 0.481 0.12204
R GILGVLMPGCPETFQSMSQFQGSR E 0 0.517 0.0861
R GETVFDDNLR E 0 0.58 0.69166
K VPILTFLQLSAMK G 0 0.538 0.17198
K LYYVTQGR G 0 0.292 0.39396
R VQIVDHR G 0 0.246 0.29134
R LNANSVVYAVR G 0 0.532 0.68356
R GGQQILADNVFK G 0 0.605 0.78042
K LFLLSLGIFLLFHCCLAIEYEQEELYECR I 0 0.163 0.05096
K GFNMEALADVLGFGMDTETAR K 0 0.552 0.04786
K GVLYENAMMAPLWR L 0 0.524 0.13704
R NTIRPQGLLLPVYTNAPK L 0 0.578 0.40726
R LTAQEPQYR L 0 0.366 0.54848
R GIPVGVLANAYR L 0 0.66 0.83882
R CAGVAALR N 0 0.29 0.48994
R EGQMVVVPQNFVVVK Q 0 0.541 0.43384
R LSQEEAR R 0 0.232 0.14388
R HFFLAGNIQR S 0 0.575 0.18694
R DEAVLFQPGSR S 0 0.694 0.9645
R GFEWVVFNTNDNALFSTAAGR T 0 0.46 0.04266
R FQDQHQK V 0 0.207 0.13406
R LTTVNSLK V 0 0.281 0.54272

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.