Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
Common buckwheat Protein: Fag e 2 | 2S Albumin
Empirical Proteotypic Peptide Explorer:
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
Sequence - 149 amino acids
MKLFIILATATLLIAATQATYPRDEGFDLGETQMSSKCMRQVKMNEPHLKKCNRYIAMDILDDKYAEALSRVEGEGCKSEESCMRGCCVAMKEMDDECVCEWMKMMVENQKGRIGERLIKEGVRDLKELPSKCGLSELECGSRGNRYFV
UniProt: Q2PS07 IUIS: Fag e 2Peptide Selector Tool
Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
Minimum length:
Maximum length:
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| K | LFIILATATLLIAATQATYPR | D | 0 | 0.412 | 0.1154 |
| R | DEGFDLGETQMSSK | C | 0 | 0.543 | 0.63494 |
| K | MNEPHLK | K | 0 | 0.245 | 0.17488 |
| R | YIAMDILDDK | Y | 0 | 0.428 | 0.36122 |
| K | YAEALSR | V | 0 | 0.244 | 0.22796 |
| R | VEGEGCK | S | 0 | 0.189 | 0.09134 |
| K | SEESCMR | G | 0 | 0.235 | 0.0975 |
| R | GCCVAMK | E | 0 | 0.223 | 0.28044 |
| K | EMDDECVCEWMK | M | 0 | 0.417 | 0.35132 |
| K | MMVENQK | G | 0 | 0.211 | 0.1883 |
| K | CGLSELECGSR | G | 0 | 0.468 | 0.45122 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.