If you found this site useful, please cite: Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

Crab Protein: Cha f 1 | Tropomyosin

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 264 amino acids

MDAIKKKMQAMKLEKDNAMDRADTLEQQNKEANLRAEKTEEEIRATQKKMQQVENELDQAQEQLSAANTKLDEKEKALQNAEGEVAALNRRIQLPEEDLERSEERLNTATTKLAEASQAADESERMRKVLENRSLSDEERMDALENQLKEARFLAEEADRKYDEVARKLAMVEADLERAEERAESGESKIVELEEELRVVGNNLKSLEVSEEKANQREETYKEQIKTLANKLKAAEARAEFAERSVQKLQKEVDRLEDELVNEK

UniProt: Q9N2R3   IUIS: Cha f 1

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1Peptide2Exp.3ESP4CONSeQ5
R LEDELVNEK $ 0 0.374 0.50822
K SLEVSEEK A 1 0.213 0.3842
K LAMVEADLER A 0 0.437 0.63148
R ADTLEQQNK E 0 0.256 0.23162
R MDALENQLK E 1 0.274 0.62192
R AESGESK I 0 0.182 0.021
R FLAEEADR K 1 0.316 0.60278
K MQQVENELDQAQEQLSAANTK L 0 0.545 0.46966
R LNTATTK L 0 0.228 0.07776
K LAEASQAADESER M 1 0.449 0.41992
R SLSDEER M 0 0.212 0.05738
K ALQNAEGEVAALNR R 0 0.678 0.84988
R VVGNNLK S 0 0.238 0.24084
R IQLPEEDLER S 0 0.499 0.70268
K IVELEEELR V 1 0.364 0.5101

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.