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Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

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Egg Protein: Gal d 3 | Ovotransferrin

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 705 amino acids

MKLILCTVLSLGIAAVCFAAPPKSVIRWCTISSPEEKKCNNLRDLTQQERISLTCVQKATYLDCIKAIANNEADAISLDGGQAFEAGLAPYKLKPIAAEVYEHTEGSTTSYYAVAVVKKGTEFTVNDLQGKTSCHTGLGRSAGWNIPIGTLLHRGAIEWEGIESGSVEQAVAKFFSASCVPGATIEQKLCRQCKGDPKTKCARNAPYSGYSGAFHCLKDGKGDVAFVKHTTVNENAPDQKDEYELLCLDGSRQPVDNYKTCNWARVAAHAVVARDDNKVEDIWSFLSKAQSDFGVDTKSDFHLFGPPGKKDPVLKDLLFKDSAIMLKRVPSLMDSQLYLGFEYYSAIQSMRKDQLTPSPRENRIQWCAVGKDEKSKCDRWSVVSNGDVECTVVDETKDCIIKIMKGEADAVALDGGLVYTAGVCGLVPVMAERYDDESQCSKTDERPASYFAVAVARKDSNVNWNNLKGKKSCHTAVGRTAGWVIPMGLIHNRTGTCNFDEYFSEGCAPGSPPNSRLCQLCQGSGGIPPEKCVASSHEKYFGYTGALRCLVEKGDVAFIQHSTVEENTGGKNKADWAKNLQMDDFELLCTDGRRANVMDYRECNLAEVPTHAVVVRPEKANKIRDLLERQEKRFGVNGSEKSKFMMFESQNKDLLFKDLTKCLFKVREGTTYKEFLGDKFYTVISSLKTCNPSDILQMCSFLEGK

UniProt: P02789   IUIS: Gal d 3

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1Peptide2Exp.3ESP4CONSeQ5
K LILCTVLSLGIAAVCFAAPPK S 0 0.459 0.13374
R WCTISSPEEK K 1 0.338 0.40668
R DLTQQER I 0 0.245 0.1449
R ISLTCVQK A 1 0.289 0.37534
K ATYLDCIK A 0 0.316 0.322
K AIANNEADAISLDGGQAFEAGLAPYK L 0 0.676 0.32128
K LKPIAAEVYEHTEGSTTSYYAVAVVK K 1 0.269 0.10836
K GTEFTVNDLQGK T 3 0.573 0.86004
K TSCHTGLGR S 1 0.386 0.23336
R SAGWNIPIGTLLHR G 2 0.709 0.42344
R GAIEWEGIESGSVEQAVAK F 4 0.414 0.45028
K FFSASCVPGATIEQK L 2 0.714 0.78184
R NAPYSGYSGAFHCLK D 0 0.579 0.4149
K GDVAFVK H 0 0.217 0.59354
K HTTVNENAPDQK D 0 0.505 0.17052
K DEYELLCLDGSR Q 0 0.59 0.4936
R QPVDNYK T 0 0.206 0.21074
R VAAHAVVAR D 0 0.483 0.44796
K VEDIWSFLSK A 1 0.516 0.22652
K AQSDFGVDTK S 2 0.382 0.76348
K SDFHLFGPPGK K 1 0.66 0.40098
K DSAIMLK R 0 0.221 0.2868
R VPSLMDSQLYLGFEYYSAIQSMR K 0 0.329 0.02334
K DQLTPSPR E 1 0.294 0.31914
R IQWCAVGK D 0 0.231 0.31326
R WSVVSNGDVECTVVDETK D 1 0.466 0.26844
K GEADAVALDGGLVYTAGVCGLVPVMAER Y 1 0.404 0.1593
R YDDESQCSK T 0 0.29 0.13766
K TDERPASYFAVAVAR K 3 0.322 0.75954
K DSNVNWNNLK G 0 0.427 0.39034
K SCHTAVGR T 0 0.304 0.18046
R TAGWVIPMGLIHNR T 0 0.561 0.26328
R TGTCNFDEYFSEGCAPGSPPNSR L 1 0.72 0.3956
R LCQLCQGSGGIPPEK C 1 0.678 0.58628
K CVASSHEK Y 0 0.281 0.14394
K YFGYTGALR C 0 0.403 0.39052
K GDVAFIQHSTVEENTGGK N 1 0.741 0.65794
K NLQMDDFELLCTDGR R 1 0.606 0.32332
R ANVMDYR E 0 0.263 0.23452
R ECNLAEVPTHAVVVRPEK A 2 0.455 0.46882
R FGVNGSEK S 0 0.249 0.31072
K FMMFESQNK D 1 0.269 0.24846
K FYTVISSLK T 3 0.388 0.30304
K TCNPSDILQMCSFLEGK $ 2 0.561 0.2231

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.

 

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