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Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

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Egg Protein: Gal d 5 | Serum Albumin

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 615 amino acids

MKWVTLISFIFLFSSATSRNLQRFARDAEHKSEIAHRYNDLKEETFKAVAMITFAQYLQRCSYEGLSKLVKDVVDLAQKCVANEDAPECSKPLPSIILDEICQVEKLRDSYGAMADCCSKADPERNECFLSFKVSQPDFVQPYQRPASDVICQEYQDNRVSFLGHFIYSVARRHPFLYAPAILSFAVDFEHALQSCCKESDVGACLDTKEIVMREKAKGVSVKQQYFCGILKQFGDRVFQARQLIYLSQKYPKAPFSEVSKFVHDSIGVHKECCEGDMVECMDDMARMMSNLCSQQDVFSGKIKDCCEKPIVERSQCIMEAEFDEKPADLPSLVEKYIEDKEVCKSFEAGHDAFMAEFVYEYSRRHPEFSIQLIMRIAKGYESLLEKCCKTDNPAECYANAQEQLNQHIKETQDVVKTNCDLLHDHGEADFLKSILIRYTKKMPQVPTDLLLETGKKMTTIGTKCCQLGEDRRMACSEGYLSIVIHDTCRKQETTPINDNVSQCCSQLYANRRPCFTAMGVDTKYVPPPFNPDMFSFDEKLCSAPAEEREVGQMKLLINLIKRKPQMTEEQIKTIADGFTAMVDKCCKQSDINTCFGEEGANLIVQSRATLGIGA

UniProt: P19121   IUIS: Gal d 5

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1 Peptide 2 Exp.3 ESP4 CONSeQ5
K WVTLISFIFLFSSATSR N 0 0.285 0.1047
K AVAMITFAQYLQR C 0 0.407 0.23114
R CSYEGLSK L 0 0.272 0.30128
K DVVDLAQK C 0 0.327 0.54464
K CVANEDAPECSKPLPSIILDEICQVEK L 0 0.509 0.2566
R DSYGAMADCCSK A 0 0.351 0.22724
R NECFLSFK V 0 0.385 0.255
K VSQPDFVQPYQRPASDVICQEYQDNR V 0 0.475 0.3177
R VSFLGHFIYSVAR R 0 0.439 0.17004
R HPFLYAPAILSFAVDFEHALQSCCK E 0 0.397 0.04588
K ESDVGACLDTK E 0 0.517 0.59246
K QQYFCGILK Q 0 0.354 0.22442
R QLIYLSQK Y 0 0.258 0.32474
K APFSEVSK F 0 0.257 0.70066
K FVHDSIGVHK E 0 0.588 0.24442
K ECCEGDMVECMDDMAR M 0 0.403 0.28656
R MMSNLCSQQDVFSGK I 0 0.452 0.30378
K DCCEKPIVER S 0 0.258 0.30696
R SQCIMEAEFDEKPADLPSLVEK Y 0 0.616 0.28406
K SFEAGHDAFMAEFVYEYSR R 0 0.533 0.04698
R HPEFSIQLIMR I 0 0.436 0.19168
K GYESLLEK C 0 0.284 0.48028
K TDNPAECYANAQEQLNQHIK E 0 0.627 0.43858
K ETQDVVK T 0 0.215 0.1076
K TNCDLLHDHGEADFLK S 0 0.659 0.28182
K MPQVPTDLLLETGK K 0 0.736 0.84166
K MTTIGTK C 0 0.215 0.20726
K CCQLGEDR R 0 0.3 0.22876
R MACSEGYLSIVIHDTCR K 0 0.486 0.11586
K QETTPINDNVSQCCSQLYANR R 0 0.56 0.22064
R RPCFTAMGVDTK Y 0 0.249 0.5434
K YVPPPFNPDMFSFDEK L 0 0.878 0.35882
K LCSAPAEER E 0 0.319 0.64684
K LLINLIK R 0 0.252 0.25772
R KPQMTEEQIK T 0 0.248 0.28718
K TIADGFTAMVDK C 0 0.46 0.6631
K QSDINTCFGEEGANLIVQSR A 0 0.601 0.12756
R ATLGIGA $ 0 0.186 0.45742

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.

 

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