If you found this site useful, please cite: Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

Hazelnut Protein: Cor a 9 | 11S Seed Storage Globulin (Legumin-Like)

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 515 amino acids

MAKLILVSFSLCLLVLFNGCLGINVGLRRQQQRYFGECNLDRLNALEPTNRIEAEACQIESWDHNDQQFQCAGVAVIRRTIEPNGLLLPQYSNAPELIYIERGRGITGVLFPGCPETFEDPQQQSQQGQRQGQGQSQRSEQDRHQKIRHFREGDIIALPAGVAHWCYNDGDSPVVTVSLLHTNNYANQLDENPRHFYLAGNPDDEHQRQGQQQFGQRRRQQQHSHGEQGEQEQQGEGNNVFSGFDAEFLADAFNVDVDTARRLQSNQDKRRNIVKVEGRLQVVRPERSRQEWERQERQERESEQERERQRRQGGRGRDVNGFEETICSLRLRENICTRSRADIYTEQVGRINTVNSNTLPVLRWLQLSAERGDLQREGLYVPHWNLNAHSVVYAIRGRARVQVVDDNGNTVFDDELRQGQVLTIPQNFAVAKRAESEGFEWVAFKTNDNAQISPLAGRTSAIRALPDDVLANAFQISREEARRLKYNRQETTLVRSSRSSSERKRRSESEGRAEA

UniProt: Q8W1C2   IUIS: Cor a 9

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1Peptide2Exp.3ESP4CONSeQ5
R ALPDDVLANAFQISR E 7 0.879 0.79128
R TIEPNGLLLPQYSNAPELIYIER G 0 0.775 0.06532
R EGLYVPHWNLNAHSVVYAIR G 0 0.456 0.07602
R WLQLSAER G 3 0.304 0.40794
R ADIYTEQVGR I 8 0.479 0.80932
R LNALEPTNR I 2 0.465 0.83564
R YFGECNLDR L 0 0.501 0.26514
R DVNGFEETICSLR L 0 0.642 0.56506
R HFYLAGNPDDEHQR Q 0 0.642 0.2427
R VQVVDDNGNTVFDDELR Q 0 0.716 0.29502
R GITGVLFPGCPETFEDPQQQSQQGQR Q 0 0.712 0.4115
K LILVSFSLCLLVLFNGCLGINVGLR R 0 0.226 0.10194
R LQSNQDK R 0 0.222 0.07686
R IEAEACQIESWDHNDQQFQCAGVAVIR R 0 0.341 0.1196
R QGQQQFGQR R 0 0.323 0.3442
R QGQVLTIPQNFAVAK R 6 0.765 0.8215
R QGQGQSQR S 0 0.258 0.18488
R QETTLVR S 0 0.265 0.31886
R LQVVRPER S 0 0.255 0.48656
K TNDNAQISPLAGR T 2 0.725 0.92298
R AESEGFEWVAFK T 0 0.505 0.42388
R INTVNSNTLPVLR W 5 0.76 0.82334

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.