Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MAKMRVRLPMLILLLGVVFLLAASIGIAYGEKDFTKNPPKEREEEEHEPRQQPRPRQQEEQEREHRREEKHDGEPSRGRSQSEESQEEEHERRREHHREREQEQQPRPQRRQEEEEEEEEWQPRRQRPQSRREEREEREQEQGSSSGSQRGGGDERRQHRERRVHREEREQEQDSRSDSRRQRNPYHFSSNRFQTYYRNRNGQIRVLERFNQRTNRLENLQNYRIIEFQSKPNTLILPKHSDADFILVVLNGRATITIVNPDKRQVYNLEQGDALRLPAGTTSYILNPDDNQNLRVAKLAIPINNPGKLYDFYPSTTKDQQSYFSGFSKNTLEATFNTRYEEIERVLLGDDELQENEKQRRGQEQSHQDEGVIVRVSKKQIQELRKHAQSSSGEGKPSESGPFNLRSNKPIYSNKFGNFYEITPDINPQFQDLNISLTFTEINEGALLLPHYNSKAIFIVVVDEGEGNYELVGIRDQQRQQDEQEEEYEQGEEEVRRYSDKLSKGDVFIIPAGHPLSINASSNLRLLGFGINANENQRNFLAGSEDNVIKQLDREVKELTFPGSIEDVERLIKNQQQSYFANAQPQQQQQREKEGRRGRRGPISSILNALY
UniProt: B8Q5G0 IUIS: Lup an 1Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| R | LPMLILLLGVVFLLAASIGIAYGEK | D | 0 | 0.23 | 0.12004 |
| R | EEEEHEPR | Q | 0 | 0.278 | 0.20404 |
| R | QQEEQER | E | 0 | 0.206 | 0.16748 |
| K | HDGEPSR | G | 0 | 0.19 | 0.0325 |
| R | SQSEESQEEEHER | R | 0 | 0.404 | 0.21626 |
| R | EQEQQPRPQR | R | 0 | 0.232 | 0.239 |
| R | QEEEEEEEEWQPR | R | 0 | 0.417 | 0.31702 |
| R | EQEQGSSSGSQR | G | 0 | 0.336 | 0.15772 |
| R | EQEQDSR | S | 0 | 0.209 | 0.09736 |
| R | NPYHFSSNR | F | 0 | 0.519 | 0.2221 |
| R | LENLQNYR | I | 0 | 0.339 | 0.36144 |
| R | IIEFQSKPNTLILPK | H | 0 | 0.331 | 0.46972 |
| K | HSDADFILVVLNGR | A | 0 | 0.757 | 0.43336 |
| R | ATITIVNPDK | R | 0 | 0.454 | 0.84964 |
| R | QVYNLEQGDALR | L | 0 | 0.629 | 0.69598 |
| R | LPAGTTSYILNPDDNQNLR | V | 0 | 0.904 | 0.29806 |
| K | LAIPINNPGK | L | 0 | 0.503 | 0.7621 |
| K | LYDFYPSTTK | D | 0 | 0.552 | 0.4217 |
| K | DQQSYFSGFSK | N | 0 | 0.523 | 0.41092 |
| K | NTLEATFNTR | Y | 1 | 0.477 | 0.62746 |
| R | VLLGDDELQENEK | Q | 0 | 0.675 | 0.58394 |
| R | GQEQSHQDEGVIVR | V | 0 | 0.631 | 0.4199 |
| K | HAQSSSGEGKPSESGPFNLR | S | 0 | 0.453 | 0.40816 |
| R | SNKPIYSNK | F | 0 | 0.229 | 0.21118 |
| K | AIFIVVVDEGEGNYELVGIR | D | 0 | 0.423 | 0.0816 |
| R | QQDEQEEEYEQGEEEVR | R | 0 | 0.417 | 0.33118 |
| K | GDVFIIPAGHPLSINASSNLR | L | 0 | 0.819 | 0.11846 |
| R | LLGFGINANENQR | N | 0 | 0.722 | 0.73672 |
| R | NFLAGSEDNVIK | Q | 0 | 0.692 | 0.82816 |
| K | ELTFPGSIEDVER | L | 0 | 0.754 | 0.86118 |
| K | NQQQSYFANAQPQQQQQR | E | 0 | 0.562 | 0.40702 |
| R | GPISSILNALY | $ | 0 | 0.352 | 0.38482 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.