If you found this site useful, please cite: Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

Milk Protein: Bos d 10 | α-s2-Casein

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 222 amino acids

MKFFIFTCLLAVALAKNTMEHVSSSEESIISQETYKQEKNMAINPSKENLCSTFCKEVVRNANEEEYSIGSSSEESAEVATEEVKITVDDKHYQKALNEINQFYQKFPQYLQYLYQGPIVLNPWDQVKRNAVPITPTLNREQLSTSEENSKKTVDMESTEVFTKKTKLTEEEKNRLNFLKKISQRYQKFALPQYLKTVYQHQKAMKPWIQPKTKVIPYVRYL

UniProt: P02663   IUIS: Bos d 10

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1Peptide2Exp.3ESP4CONSeQ5
K TVYQHQK A 1 0.22 0.0863
K ENLCSTFCK E 2 0.378 0.25688
K NMAINPSK E 0 0.219 0.41102
R NAVPITPTLNR E 11 0.693 0.87576
K ALNEINQFYQK F 6 0.479 0.41192
R NANEEEYSIGSSSEESAEVATEEVK I 0 0.306 0.42088
K TVDMESTEVFTK K 2 0.436 0.55488
R EQLSTSEENSK K 0 0.296 0.16536
K FFIFTCLLAVALAK N 0 0.355 0.2363
K NTMEHVSSSEESIISQETYK Q 0 0.382 0.36826
K FPQYLQYLYQGPIVLNPWDQVK R 1 0.556 0.16636
K AMKPWIQPK T 0 0.216 0.35832
K FALPQYLK T 7 0.333 0.36948

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.