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Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

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Milk Protein: Bos d 6 | Serum Albumin

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 607 amino acids

MKWVTFISLLLLFSSAYSRGVFRRDTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA

UniProt: P02769   IUIS: Bos d 6

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1 Peptide 2 Exp.3 ESP4 CONSeQ5
K WVTFISLLLLFSSAYSR G 0 0.192 0.08522
K DLGEEHFK G 0 0.3 0.25452
K GLVLIAFSQYLQQCPFDEHVK L 0 0.551 0.01948
K LVNELTEFAK T 0 0.533 0.58414
K TCVADESHAGCEK S 0 0.568 0.27278
K SLHTLFGDELCK V 0 0.661 0.33274
R ETYGDMADCCEK Q 0 0.414 0.23426
R NECFLSHK D 0 0.336 0.19066
K DDSPDLPK L 0 0.172 0.15804
K LKPDPNTLCDEFK A 0 0.323 0.55512
K YLYEIAR R 0 0.261 0.20528
R HPYFYAPELLYYANK Y 0 0.48 0.18012
K YNGVFQECCQAEDK G 0 0.524 0.26712
K GACLLPK I 0 0.182 0.3486
K VLASSAR Q 0 0.226 0.1753
K AEFVEVTK L 0 0.253 0.50496
K LVTDLTK V 0 0.242 0.29902
K ECCHGDLLECADDR A 0 0.531 0.28436
K YICDNQDTISSK L 0 0.532 0.28064
K ECCDKPLLEK S 0 0.248 0.3755
K SHCIAEVEK D 0 0.358 0.2777
K DAIPENLPPLTADFAEDK D 0 0.829 0.56814
K DAFLGSFLYEYSR R 0 0.582 0.16252
R HPEYAVSVLLR L 0 0.639 0.46918
K EYEATLEECCAK D 0 0.465 0.4495
K DDPHACYSTVFDK L 0 0.643 0.28234
K HLVDEPQNLIK Q 0 0.636 0.67586
K QNCDQFEK L 0 0.269 0.2779
K LGEYGFQNALIVR Y 0 0.605 0.3024
K VPQVSTPTLVEVSR S 0 0.762 0.73418
R CCTKPESER M 0 0.223 0.16896
R MPCTEDYLSLILNR L 0 0.621 0.2753
R LCVLHEK T 0 0.266 0.1603
K CCTESLVNR R 0 0.401 0.30998
R RPCFSALTPDETYVPK A 0 0.502 0.60272
K LFTFHADICTLPDTEK Q 0 0.772 0.1548
K QTALVELLK H 0 0.379 0.46916
K ATEEQLK T 0 0.217 0.0811
K TVMENFVAFVDK C 0 0.54 0.19302
K CCAADDK E 0 0.307 0.13622
K EACFAVEGPK L 0 0.361 0.75852
K LVVSTQTALA $ 0 0.397 0.383

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.

 

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