Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MKLLILTCLVAVALARPKHPIKHQGLPQEVLNENLLRFFVAPFPEVFGKEKVNELSKDIGSESTEDQAMEDIKQMEAESISSSEEIVPNSVEQKHIQKEDVPSERYLGYLEQLLRLKKYKVPQLEIVPNSAEERLHSMKEGIHAQQKEPMIGVNQELAYFYPELFRQFYQLDAYPSGAWYYVPLGTQYTDAPSFSDIPNPIGSENSEKTTMPLW
UniProt: P02662 IUIS: Bos d 9Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| K | LLILTCLVAVALARPK | H | 0 | 0.237 | 0.28566 |
| K | HQGLPQEVLNENLLR | F | 14 | 0.759 | 0.54854 |
| R | FFVAPFPEVFGK | E | 24 | 0.622 | 0.3876 |
| K | DIGSESTEDQAMEDIK | Q | 1 | 0.498 | 0.51994 |
| K | QMEAESISSSEEIVPNSVEQK | H | 0 | 0.377 | 0.41922 |
| K | EDVPSER | Y | 1 | 0.181 | 0.07756 |
| R | YLGYLEQLLR | L | 23 | 0.382 | 0.25618 |
| K | VPQLEIVPNSAEER | L | 2 | 0.792 | 0.88926 |
| K | EGIHAQQK | E | 1 | 0.233 | 0.1783 |
| K | EPMIGVNQELAYFYPELFR | Q | 2 | 0.683 | 0.05114 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.