Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
Pecan Protein: Car i 2 | Vicilin-like Seed Storage Protein; 7S Globulin
Empirical Proteotypic Peptide Explorer:
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
Sequence - 792 amino acids
MVTKAKIPLFLFLSALFLALVCSSLALETEDLSNELNPHHDPESHRWEFQQCQERCQHEERGQRQAQQCQRRCEEQLREREREREREEIVDPREPRKQYEQCRETCEKQDPRQQPQCERRCERQFQEQQERERRERRRGRDDDDKENPRDPREQYRQCEEHCRRQGQGQRQQQQCQSRCEERFEEEQRRQEERERRRGRDNDDEENPRDPREQYRQCQEHCRRQGQGQRQQQQCQSRCEERLEEEQRKQEERERRRGRDEDDQNPRDPEQRYEQCQQQCERQRRGQEQQLCRRRCEQQRQQEERERQRGRDRQDPQQQYHRCQRRCQTQEQSPERQRQCQQRCERQYKEQQGREWGPDQASPRRESRGREEEQQRHNPYYFHSQGLRSRHESGEGEVKYLERFTERTELLRGIENYRVVILEANPNTFVLPYHKDAESVIVVTRGRATLTFVSQERRESFNLEYGDVIRVPAGATEYVINQDSNERLEMVKLLQPVNNPGQFREYYAAGAQSTESYLRVFSNDILVAALNTPRDRLERFFDQQEQREGVIIRASQEKLRALSQHAMSAGQRPWGRRSSGGPISLKSQRSSYSNQFGQFFEACPEEHRQLQEMDVLVNYAEIKRGAMMVPHYNSKATVVVYVVEGTGRFEMACPHDVSSQSYEYKGRREQEEEESSTGQFQKVTARLARGDIFVIPAGHPIAITASQNENLRLVGFGINGKNNQRNFLAGQNNIINQLEREAKELSFNMPREEIEEIFERQVESYFVPMERQSRRGQGRDHPLASILDFAGFF
UniProt: B3STU4 IUIS: Car i 2Peptide Selector Tool
Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
Minimum length:
Maximum length:
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| R | WEFQQCQER | C | 0 | 0.0 | 0.0 |
| R | QAQQCQR | R | 0 | 0.0 | 0.0 |
| R | EEIVDPR | E | 0 | 0.0 | 0.0 |
| R | QQPQCER | R | 0 | 0.0 | 0.0 |
| R | QFQEQQER | E | 0 | 0.0 | 0.0 |
| R | QCEEHCR | R | 0 | 0.0 | 0.0 |
| R | QQQQCQSR | C | 0 | 0.0 | 0.0 |
| R | DNDDEENPR | D | 0 | 0.0 | 0.0 |
| R | QCQEHCR | R | 0 | 0.0 | 0.0 |
| R | DEDDQNPR | D | 0 | 0.0 | 0.0 |
| R | YEQCQQQCER | Q | 0 | 0.303 | 0.28522 |
| R | GQEQQLCR | R | 0 | 0.0 | 0.0 |
| R | QDPQQQYHR | C | 0 | 0.248 | 0.24776 |
| R | CQTQEQSPER | Q | 0 | 0.0 | 0.0 |
| R | EWGPDQASPR | R | 0 | 0.0 | 0.0 |
| R | HNPYYFHSQGLR | S | 0 | 0.0 | 0.0 |
| R | HESGEGEVK | Y | 0 | 0.0 | 0.0 |
| R | VVILEANPNTFVLPYHK | D | 0 | 0.0 | 0.0 |
| K | DAESVIVVTR | G | 0 | 0.52 | 0.71566 |
| R | ATLTFVSQER | R | 2 | 0.0 | 0.0 |
| R | ESFNLEYGDVIR | V | 0 | 0.0 | 0.0 |
| R | VPAGATEYVINQDSNER | L | 0 | 0.747 | 0.74336 |
| K | LLQPVNNPGQFR | E | 0 | 0.791 | 0.74014 |
| R | EYYAAGAQSTESYLR | V | 0 | 0.0 | 0.0 |
| R | VFSNDILVAALNTPR | D | 0 | 0.818 | 0.64274 |
| R | FFDQQEQR | E | 0 | 0.307 | 0.3049 |
| R | ALSQHAMSAGQRPWGR | R | 0 | 0.212 | 0.3027 |
| R | SSGGPISLK | S | 0 | 0.271 | 0.4624 |
| R | SSYSNQFGQFFEACPEEHR | Q | 0 | 0.0 | 0.0 |
| R | QLQEMDVLVNYAEIK | R | 0 | 0.554 | 0.27588 |
| R | GAMMVPHYNSK | A | 0 | 0.346 | 0.2431 |
| K | ATVVVYVVEGTGR | F | 0 | 0.431 | 0.65836 |
| R | FEMACPHDVSSQSYEYK | G | 0 | 0.0 | 0.0 |
| R | EQEEEESSTGQFQK | V | 0 | 0.0 | 0.0 |
| R | GDIFVIPAGHPIAITASQNENLR | L | 0 | 0.87 | 0.09846 |
| R | LVGFGINGK | N | 2 | 0.0 | 0.0 |
| R | NFLAGQNNIINQLER | E | 2 | 0.0 | 0.0 |
| K | ELSFNMPR | E | 0 | 0.299 | 0.581 |
| R | EEIEEIFER | Q | 0 | 0.0 | 0.0 |
| R | QVESYFVPMER | Q | 1 | 0.0 | 0.0 |
| R | DHPLASILDFAGFF | $ | 0 | 0.0 | 0.0 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.