If you found this site useful, please cite: Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

Pistachio Protein: Pis v 2 | 11S Globulin Subunit

Isoform:

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 496 amino acids

MGYSSLLSFSLGFLLLFHCSFAQIEQVVNSQQRQQQQRFQTQCQIQNLNALEPKRRIESEAGVTEFWDQNEEQLQCANVAVFRHTIQSRGLLVPSYDNAPELVYVVQGSGIHGAVFPGCPETFQEESQSRSRSERSQQSGEQHQKVRPIQEGDVIALPAGVAHWIYNNGQSKLVLVALADVGNSENQLDQYLRKFVLGGSPQQEIQGSGQSRSRSQSQSSRRGQQGQQSNNILSAFDEEILAQSFNIDTQLARRLQKEKRQRGIIVRVQEDLEVLSPHRQEQEQEYEEERERRQRNGLEETFCTMTLKYNINDPSRADVYNPRGGRVSSVNALNLPILRFLQLSAKKGVLHRDAILAPHWNVNAHSIVYITRGNGRIQIVSENGESVFDEEIREGQLVVVPQNFAVVKRASSDKFEWVSFKTNGLSQTSQLAGRVSVFRALPLDVIKNSFDISREDARRLKESRSETTIFAPGSSSQRKSQSERERQREREEREIH

UniProt: B7P073   IUIS: Pis v 2

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 472 amino acids

MGYSSLLSFSLGFLLLFHCSFAQIEQVVNSQQRQQQQRFQTQCQIQNLNALEPKRRIESEAGVTEFWDQNEEQLQCANVAVFRHTIQSRGLLVPSYNNAPELVYVVQGSGIHGAVFPGCPETFQEESQSQSRSQHSRSERSQQSGEQHQKVRHIREGDIIALPAGVAHWIYNNGQSKLVLVALADVGNSENQLDQYLRKFVLGGSPQQEIQGGGQSWSQSRSSRKGQQSNNILSAFDEEILAQSFNIDTQLVKKLQREEKQRGIIVRVKEDLQVLSPQRQEKEYSDNGLEETFCTMTLKLNINDPSRADVYNPRGGRVTSINALNLPILRFLQLSVEKGVLYQNAIMAPHWNMNAHSIVYITRGNGRMQIVSENGESVFDEEIREGQLVVVPQNFAVVKRASSDGFEWVSFKTNGLAKISQLAGRISVMRGLPLDVIQNSFDISREDAWNLKESRSEMTIFAPGSRSQRQRN

UniProt: B7P074   IUIS: Pis v 2

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1Peptide2Exp.3ESP4CONSeQ5
K YNINDPSR A 0 0.29 0.2944
K LNINDPSR A 0 0.276 0.53608
K NSFDISR E 1 0.276 0.2097
R EDAWNLK E 0 0.205 0.20956
R MQIVSENGESVFDEEIR E 0 0.484 0.20988
R IQIVSENGESVFDEEIR E 0 0.505 0.225
R QEQEQEYEEER E 0 0.338 0.30324
R GLPLDVIQNSFDISR E 0 0.854 0.69864
R VTSINALNLPILR F 2 0.71 0.4509
R VSSVNALNLPILR F 0 0.686 0.61468
K GVLYQNAIMAPHWNMNAHSIVYITR G 0 0.286 0.04286
R DAILAPHWNVNAHSIVYITR G 0 0.481 0.10918
R ADVYNPR G 0 0.251 0.22844
R FLQLSVEK G 0 0.312 0.32274
R IESEAGVTEFWDQNEEQLQCANVAVFR H 0 0.325 0.07578
K ISQLAGR I 0 0.249 0.2126
K LVLVALADVGNSENQLDQYLR K 0 0.609 0.03012
K GQQSNNILSAFDEEILAQSFNIDTQLVK K 0 0.389 0.0424
R FLQLSAK K 0 0.27 0.25434
R SETTIFAPGSSSQR K 0 0.675 0.71428
K VRPIQEGDVIALPAGVAHWIYNNGQSK L 0 0.347 0.09898
K EYSDNGLEETFCTMTLK L 0 0.565 0.1404
R EGDIIALPAGVAHWIYNNGQSK L 0 0.685 0.08282
R ALPLDVIK N 2 0.352 0.62858
K EDLQVLSPQR Q 0 0.572 0.77516
R VQEDLEVLSPHR Q 0 0.691 0.71836
R SQSQSSR R 0 0.206 0.04908
R FQTQCQIQNLNALEPK R 0 0.665 0.42534
R EGQLVVVPQNFAVVK R 1 0.669 0.68694
K FVLGGSPQQEIQGGGQSWSQSR S 0 0.457 0.39852
K FVLGGSPQQEIQGSGQSR S 0 0.707 0.68442
R SEMTIFAPGSR S 0 0.519 0.91658
K FEWVSFK T 0 0.238 0.18918
R ASSDGFEWVSFK T 0 0.601 0.51038
K TNGLSQTSQLAGR V 1 0.65 0.57162
R SQQSGEQHQK V 0 0.217 0.16696
R NGLEETFCTMTLK Y 0 0.512 0.44812

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.