Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MVAFKFLLALSLSLLVSAAIAQTREPRLTQGQQCRFQRISGAQPSLRIQSEGGTTELWDERQEQFQCAGIVAMRSTIRPNGLSLPNYHPSPRLVYIERGQGLISIMVPGCAETYQVHRSQRTMERTEASEQQDRGSVRDLHQKVHRLRQGDIVAIPSGAAHWCYNDGSEDLVAVSINDVNHLSNQLDQKFRAFYLAGGVPRSGEQEQQARQTFHNIFRAFDAELLSEAFNVPQETIRRMQSEEEERGLIVMARERMTFVRPDEEEGEQEHRGRQLDNGLEETFCTMKFRTNVESRREADIFSRQAGRVHVVDRNKLPILKYMDLSAEKGNLYSNALVSPDWSMTGHTIVYVTRGDAQVQVVDHNGQALMNDRVNQGEMFVVPQYYTSTARAGNNGFEWVAFKTTGSPMRSPLAGYTSVIRAMPLQVITNSYQISPNQAQALKMNRGSQSFLLSPGGRRS
UniProt: Q9XHP0 IUIS: Ses i 6Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| K | FLLALSLSLLVSAAIAQTR | E | 0 | 0.356 | 0.14532 |
| R | LTQGQQCR | F | 0 | 0.255 | 0.26022 |
| R | ISGAQPSLR | I | 1 | 0.372 | 0.89282 |
| R | IQSEGGTTELWDER | Q | 0 | 0.549 | 0.71622 |
| R | QEQFQCAGIVAMR | S | 0 | 0.452 | 0.41762 |
| R | STIRPNGLSLPNYHPSPR | L | 0 | 0.466 | 0.3575 |
| R | GQGLISIMVPGCAETYQVHR | S | 0 | 0.62 | 0.1125 |
| R | TEASEQQDR | G | 0 | 0.237 | 0.14336 |
| R | AFYLAGGVPR | S | 1 | 0.535 | 0.59232 |
| R | SGEQEQQAR | Q | 0 | 0.23 | 0.17392 |
| R | QTFHNIFR | A | 0 | 0.404 | 0.13278 |
| R | AFDAELLSEAFNVPQETIR | R | 0 | 0.806 | 0.05676 |
| R | MQSEEEER | G | 0 | 0.226 | 0.23042 |
| R | GLIVMAR | E | 0 | 0.21 | 0.49376 |
| R | MTFVRPDEEEGEQEHR | G | 0 | 0.297 | 0.32722 |
| R | QLDNGLEETFCTMK | F | 0 | 0.524 | 0.501 |
| R | EADIFSR | Q | 0 | 0.259 | 0.3613 |
| K | YMDLSAEK | G | 0 | 0.269 | 0.45002 |
| K | GNLYSNALVSPDWSMTGHTIVYVTR | G | 0 | 0.382 | 0.05604 |
| R | GDAQVQVVDHNGQALMNDR | V | 0 | 0.563 | 0.45162 |
| R | VNQGEMFVVPQYYTSTAR | A | 0 | 0.601 | 0.12464 |
| R | AGNNGFEWVAFK | T | 0 | 0.573 | 0.45946 |
| K | TTGSPMR | S | 0 | 0.259 | 0.08924 |
| R | SPLAGYTSVIR | A | 1 | 0.644 | 0.9057 |
| R | AMPLQVITNSYQISPNQAQALK | M | 0 | 0.717 | 0.1338 |
| R | GSQSFLLSPGGR | R | 0 | 0.65 | 0.6474 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.