Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
VEKEECEEGEIPRPRPRPQHPEREPQQPGEKEEDEDEQPRPIPFPRPQPRQEEEHEQREEQEWPRKEEKRGEKGSEEEDEDEDEEQDERQFPFPRPPHQKEERKQEEDEDEEQQRESEESEDSELRRHKNKNPFLFGSNRFETLFKNQYGRIRVLQRFNQRSPQLQNLRDYRILEFNSKPNTLLLPNHADADYLIVILNGTAILSLVNNDDRDSYRLQSGDALRVPSGTTYYVVNPDNNENLRLITLAIPVNKPGRFESFFLSSTEAQQSYLQGFSRNILEASYDTKFEEINKVLFSREEGQQQGEQRLQESVIVEISKEQIRALSKRAKSSSRKTISSEDKPFNLRSRDPIYSNKLGKFFEITPEKNPQLRDLDIFLSIVDMNEGALLLPHFNSKAIVILVINEGDANIELVGLKEQQQEQQQEEQPLEVRKYRAELSEQDIFVIPAGYPVVVNATSNLNFFAIGINAENNQRNFLAGSQDNVISQIPSQVQELAFPGSAQAVEKLLKNQRESYFVDAQPKKKEEGNKGRKGPLSSILRAFY
UniProt: O22120 IUIS: Gly m 5Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
---|---|---|---|---|---|
K | EECEEGEIPRPRPRPQHPER | E | 0 | 0.365 | 0.32986 |
R | EPQQPGEK | E | 1 | 0.206 | 0.14966 |
K | EEDEDEQPRPIPFPRPQPR | Q | 0 | 0.549 | 0.36626 |
R | QEEEHEQR | E | 1 | 0.211 | 0.19714 |
R | EEQEWPR | K | 1 | 0.251 | 0.16734 |
K | GSEEEDEDEDEEQDER | Q | 2 | 0.391 | 0.23484 |
R | QFPFPRPPHQK | E | 3 | 0.204 | 0.40308 |
K | QEEDEDEEQQR | E | 2 | 0.312 | 0.26724 |
R | ESEESEDSELR | R | 3 | 0.312 | 0.20436 |
K | NPFLFGSNR | F | 3 | 0.586 | 0.51772 |
R | SPQLQNLR | D | 3 | 0.307 | 0.53638 |
R | LQSGDALR | V | 1 | 0.275 | 0.61718 |
R | VPSGTTYYVVNPDNNENLR | L | 5 | 0.722 | 0.27154 |
R | LITLAIPVNKPGR | F | 7 | 0.38 | 0.63246 |
R | FESFFLSSTEAQQSYLQGFSR | N | 3 | 0.39 | 0.08044 |
R | NILEASYDTK | F | 3 | 0.476 | 0.77914 |
R | EEGQQQGEQR | L | 3 | 0.265 | 0.22268 |
R | LQESVIVEISK | E | 4 | 0.496 | 0.52658 |
K | TISSEDKPFNLR | S | 5 | 0.249 | 0.72024 |
R | DPIYSNK | L | 2 | 0.211 | 0.2019 |
K | FFEITPEK | N | 3 | 0.325 | 0.4369 |
R | DLDIFLSIVDMNEGALLLPHFNSK | A | 4 | 0.586 | 0.02084 |
K | AIVILVINEGDANIELVGLK | E | 3 | 0.483 | 0.11316 |
K | EQQQEQQQEEQPLEVR | K | 4 | 0.517 | 0.39196 |
R | ESYFVDAQPK | K | 5 | 0.507 | 0.71274 |
K | GPLSSILR | A | 0 | 0.336 | 0.62248 |
^ | VEEEEECEEGQIPRPRPQHPER | E | 0 | 0.494 | 0.36234 |
K | EEDEGEQPRPFPFPRPR | Q | 0 | 0.402 | 0.36612 |
R | QPHQEEEHEQK | E | 0 | 0.266 | 0.23436 |
K | EEHEWHR | K | 0 | 0.175 | 0.11114 |
K | GSEEEQDER | E | 2 | 0.209 | 0.1296 |
R | EHPRPHQPHQK | E | 1 | 0.154 | 0.23408 |
K | ESEEEEEDQDEDEEQDK | E | 2 | 0.451 | 0.28198 |
K | ESQESEGSESQR | E | 1 | 0.28 | 0.15806 |
K | NPFHFNSK | R | 2 | 0.35 | 0.37964 |
K | NQYGHVR | V | 1 | 0.28 | 0.09148 |
R | SQQLQNLR | D | 3 | 0.273 | 0.3846 |
R | DSYNLQSGDALR | V | 4 | 0.653 | 0.6371 |
R | VPAGTTYYVVNPDNDENLR | M | 2 | 0.766 | 0.2374 |
R | MITLAIPVNKPGR | F | 4 | 0.347 | 0.6558 |
R | FESFFLSSTQAQQSYLQGFSK | N | 2 | 0.395 | 0.09892 |
K | NILEASYDTK | F | 3 | 0.476 | 0.77914 |
R | EEGQQQGEER | L | 3 | 0.249 | 0.20224 |
R | LQESVIVEISK | K | 4 | 0.496 | 0.52658 |
K | TISSEDKPFNLR | S | 5 | 0.249 | 0.72024 |
R | DPIYSNK | L | 2 | 0.211 | 0.2019 |
K | LFEITPEK | N | 1 | 0.307 | 0.69788 |
R | DLDVFLSVVDMNEGALFLPHFNSK | A | 2 | 0.582 | 0.02366 |
K | AIVVLVINEGEANIELVGIK | E | 3 | 0.439 | 0.13348 |
R | QQQEEQPLEVR | K | 5 | 0.391 | 0.3806 |
R | NFLAGSK | D | 2 | 0.234 | 0.13864 |
K | DNVISQIPSQVQELAFPGSAK | D | 2 | 0.842 | 0.23926 |
K | DIENLIK | S | 2 | 0.241 | 0.33982 |
K | SQSESYFVDAQPQQK | E | 2 | 0.597 | 0.45888 |
K | GPLSSILR | A | 0 | 0.336 | 0.62248 |
R | FPLLVLLGTVFLASVCVSLK | V | 0 | 0.377 | 0.11506 |
R | EDENNPFYLR | S | 1 | 0.595 | 0.41844 |
R | SSNSFQTLFENQNGR | I | 1 | 0.684 | 0.44082 |
R | SPQLENLR | D | 2 | 0.321 | 0.58208 |
R | IVQFQSKPNTILLPHHADADFLLFVLSGR | A | 1 | 0.173 | 0.04858 |
R | AILTLVNNDDR | D | 2 | 0.735 | 0.78706 |
R | DSYNLHPGDAQR | I | 2 | 0.618 | 0.2405 |
R | IPAGTTYYLVNPHDHQNLK | I | 1 | 0.668 | 0.1727 |
K | LAIPVNKPGR | Y | 1 | 0.298 | 0.5279 |
R | VLLGEEEEQR | Q | 1 | 0.458 | 0.60052 |
R | QQEGVIVELSK | E | 2 | 0.462 | 0.68176 |
K | TISSEDEPFNLR | S | 2 | 0.676 | 0.86936 |
R | NPIYSNNFGK | F | 2 | 0.503 | 0.4255 |
K | FFEITPEK | N | 3 | 0.325 | 0.4369 |
R | DLDIFLSSVDINEGALLLPHFNSK | A | 2 | 0.713 | 0.02604 |
K | AIVILVINEGDANIELVGIK | E | 2 | 0.47 | 0.12148 |
K | QEEEPLEVQR | Y | 2 | 0.382 | 0.40604 |
R | NFLAGEK | D | 1 | 0.243 | 0.15904 |
R | QVQELAFPGSAQDVER | L | 3 | 0.825 | 0.80748 |
R | ESYFVDAQPQQK | E | 1 | 0.522 | 0.53044 |
K | GPFPSILGALY | $ | 0 | 0.427 | 0.40336 |
R | FPLLVLLGTVFLASVCVSLK | V | 0 | 0.377 | 0.11506 |
R | EDENNPFYFR | S | 1 | 0.606 | 0.35834 |
R | SSNSFQTLFENQNGR | I | 1 | 0.684 | 0.44082 |
R | SPQLENLR | D | 2 | 0.321 | 0.58208 |
R | IVQFQSKPNTILLPHHADADFLLFVLSGR | A | 1 | 0.173 | 0.04858 |
R | AILTLVNNDDR | D | 2 | 0.735 | 0.78706 |
R | DSYNLHPGDAQR | I | 2 | 0.618 | 0.2405 |
R | IPAGTTYYLVNPHDHQNLK | I | 1 | 0.668 | 0.1727 |
K | LAIPVNKPGR | Y | 1 | 0.298 | 0.5279 |
R | VLFGEEEEQR | Q | 2 | 0.482 | 0.5588 |
R | QQEGVIVELSK | E | 2 | 0.462 | 0.68176 |
K | TISSEDEPFNLR | S | 2 | 0.676 | 0.86936 |
R | NPIYSNNFGK | F | 2 | 0.503 | 0.4255 |
K | FFEITPEK | N | 3 | 0.325 | 0.4369 |
R | DLDIFLSSVDINEGALLLPHFNSK | A | 2 | 0.713 | 0.02604 |
K | AIVILVINEGDANIELVGIK | E | 2 | 0.47 | 0.12148 |
K | QEEEPLEVQR | Y | 2 | 0.382 | 0.40604 |
R | NFLAGEK | D | 1 | 0.243 | 0.15904 |
R | QVQELAFPGSAQDVER | L | 3 | 0.825 | 0.80748 |
R | ESYFVDAQPQQK | E | 1 | 0.522 | 0.53044 |
K | GPFPSILGALY | $ | 0 | 0.427 | 0.40336 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.