Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MASEQLARRENTTTEKEIHVEKHRVPKMATHFEHLAEQAKESDITAGKDTPQGSIEALQAGERVKDHAGKAMGDIGGRGKARETHELGAHFESLADKVTDHAAANVVGNKESQREARGGVRDVGKFEMRTEGGEKGNKDRPELKTRTREVIGRTEKERGRESGGQVVAEKGRETETARGRVGAENEGARTTAVITCTLEKGGGTQKPIREEERESESERSAWEQISNYSDQATQGVKEKYERAKQAASETLNTTTQTAQEKSAQAKNLAAQAKDATLEKGQQGYAVTKDTISSAAKTASEKTAPVAEKAKDYTLQAAEKAKSAGGTTASYVGEKAVQAKDVAVESGKSAAGYAAKVAADLRDKATAVGWAAAHFSAEKTVEGTKAAAHVVEGAAGYAGHKAAELASMSAGAVKGLAASAGETAKEYTAKKKEEAQRELEAKKPSQPQEAEERPSEGIGETVRQYAQKPKPSERNPQKEGTGSIVFTAIGETVSSAGEKVKKPFKNTTGGESEGGGGKEEGKSVIGKSLTSIGEKLGDAKQREELLDNVTGNITEGGGEVLGAVGETVAEIGQNMMKPAEIVQERAHVRQAGGVLDAIGETIAEIAETTRVMVSGEDERVLRQSVVLETRVTGRAKHEEGSHGA
UniProt: C6K8D1 IUIS: Gly m 7Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
---|---|---|---|---|---|
^ | MASEQLAR | R | 0 | 0.235 | 0.67152 |
R | ENTTTEK | E | 0 | 0.178 | 0.0495 |
K | MATHFEHLAEQAK | E | 0 | 0.398 | 0.29778 |
K | ESDITAGK | D | 0 | 0.221 | 0.1769 |
K | DTPQGSIEALQAGER | V | 0 | 0.789 | 0.86966 |
K | AMGDIGGR | G | 0 | 0.234 | 0.29854 |
R | ETHELGAHFESLADK | V | 0 | 0.657 | 0.43754 |
K | VTDHAAANVVGNK | E | 0 | 0.701 | 0.51948 |
R | ESGGQVVAEK | G | 0 | 0.329 | 0.51412 |
R | VGAENEGAR | T | 0 | 0.263 | 0.36616 |
R | TTAVITCTLEK | G | 0 | 0.438 | 0.55868 |
K | GGGTQKPIR | E | 0 | 0.236 | 0.24038 |
R | SAWEQISNYSDQATQGVK | E | 0 | 0.545 | 0.41946 |
K | QAASETLNTTTQTAQEK | S | 0 | 0.66 | 0.38034 |
K | NLAAQAK | D | 0 | 0.225 | 0.09526 |
K | GQQGYAVTK | D | 0 | 0.275 | 0.50392 |
K | DTISSAAK | T | 0 | 0.238 | 0.2151 |
K | TAPVAEK | A | 0 | 0.187 | 0.11696 |
K | DYTLQAAEK | A | 0 | 0.324 | 0.61882 |
K | SAGGTTASYVGEK | A | 0 | 0.531 | 0.4935 |
K | DVAVESGK | S | 0 | 0.247 | 0.24392 |
K | SAAGYAAK | V | 0 | 0.205 | 0.25376 |
K | ATAVGWAAAHFSAEK | T | 0 | 0.567 | 0.59564 |
K | AAAHVVEGAAGYAGHK | A | 0 | 0.544 | 0.4747 |
K | AAELASMSAGAVK | G | 0 | 0.347 | 0.73054 |
K | GLAASAGETAK | E | 0 | 0.325 | 0.5245 |
K | KPSQPQEAEERPSEGIGETVR | Q | 0 | 0.331 | 0.39584 |
R | QYAQKPKPSER | N | 0 | 0.225 | 0.18032 |
K | EGTGSIVFTAIGETVSSAGEK | V | 0 | 0.494 | 0.42636 |
K | NTTGGESEGGGGK | E | 0 | 0.439 | 0.2026 |
K | SLTSIGEK | L | 0 | 0.264 | 0.46596 |
R | QAGGVLDAIGETIAEIAETTR | V | 0 | 0.652 | 0.31836 |
R | VMVSGEDER | V | 0 | 0.292 | 0.57484 |
R | QSVVLETR | V | 0 | 0.351 | 0.63252 |
K | HEEGSHGA | $ | 0 | 0.336 | 0.13164 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.