Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
GRDRQDPQQQYHRCQRRCQIQEQSPERQRQCQQRCERQYKEQQGRERGPEASPRRESKGREEEQQRHNPYYFHSQSIRSRHESEEGEVKYLERFAERTELLRGIENYRVVILDANPNTFMLPHHKDAESVIVVTRGRATLTLVSQETRESFNLECGDVIRVPAGATEYVINQDSNERLEMVKLLQPVNNPGQVREYYAAGAKSPDQSYLRVFSNDILVAALNTPRDRLERFFDQQEQREGVIIRASQEKLRALSQHAMSAGQRPWGRRSSGGPISLKSERPSYSNQFGQFFEACPEEHRQLQEMDVLVNYAEIKRGAMMVPHYNSKATVVVYVVEGTGRYEMACPHVSSQSFEDQGRREQEEEESTGRFQKVTARLARGDIFVIPAGHPIAITASQNENLRLLGFGINGENNQRNFLAGQNSIINQLEREAKELSFNMPREEIEEIFESQMESYFVPTERQSRRGQGRDHPLASILGFAFF
UniProt: Q7Y1C1 IUIS: Jug n 2Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| R | QDPQQQYHR | C | 0 | 0.248 | 0.24776 |
| R | CQIQEQSPER | Q | 0 | 0.305 | 0.34526 |
| R | GPEASPR | R | 0 | 0.167 | 0.1091 |
| R | HNPYYFHSQSIR | S | 0 | 0.48 | 0.14444 |
| R | HESEEGEVK | Y | 0 | 0.241 | 0.13812 |
| R | VVILDANPNTFMLPHHK | D | 0 | 0.565 | 0.17264 |
| K | DAESVIVVTR | G | 0 | 0.52 | 0.71566 |
| R | ATLTLVSQETR | E | 0 | 0.568 | 0.75268 |
| R | ESFNLECGDVIR | V | 0 | 0.623 | 0.5159 |
| R | VPAGATEYVINQDSNER | L | 0 | 0.747 | 0.74336 |
| K | LLQPVNNPGQVR | E | 0 | 0.75 | 0.85932 |
| R | EYYAAGAK | S | 0 | 0.241 | 0.391 |
| K | SPDQSYLR | V | 0 | 0.308 | 0.38992 |
| R | VFSNDILVAALNTPR | D | 0 | 0.818 | 0.64274 |
| R | FFDQQEQR | E | 0 | 0.307 | 0.3049 |
| R | ALSQHAMSAGQRPWGR | R | 0 | 0.212 | 0.3027 |
| R | SSGGPISLK | S | 0 | 0.271 | 0.4624 |
| K | SERPSYSNQFGQFFEACPEEHR | Q | 0 | 0.391 | 0.34902 |
| R | QLQEMDVLVNYAEIK | R | 0 | 0.554 | 0.27588 |
| R | GAMMVPHYNSK | A | 0 | 0.346 | 0.2431 |
| K | ATVVVYVVEGTGR | Y | 0 | 0.431 | 0.65836 |
| R | YEMACPHVSSQSFEDQGR | R | 0 | 0.545 | 0.2716 |
| R | EQEEEESTGR | F | 0 | 0.233 | 0.17106 |
| R | GDIFVIPAGHPIAITASQNENLR | L | 0 | 0.87 | 0.09846 |
| R | LLGFGINGENNQR | N | 0 | 0.715 | 0.6153 |
| R | NFLAGQNSIINQLER | E | 0 | 0.719 | 0.52682 |
| K | ELSFNMPR | E | 0 | 0.299 | 0.581 |
| R | EEIEEIFESQMESYFVPTER | Q | 0 | 0.482 | 0.21098 |
| R | DHPLASILGFAFF | $ | 0 | 0.627 | 0.16244 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.