Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
MRGRVSPLMLLLGILVLASVSATHAKSSPYQKKTENPCAQRCLQSCQQEPDDLKQKACESRCTKLEYDPRCVYDPRGHTGTTNQRSPPGERTRGRQPGDYDDDRRQPRREEGGRWGPAGPREREREEDWRQPREDWRRPSHQQPRKIRPEGREGEQEWGTPGSHVREETSRNNPFYFPSRRFSTRYGNQNGRIRVLQRFDQRSRQFQNLQNHRIVQIEAKPNTLVLPKHADADNILVIQQGQATVTVANGNNRKSFNLDEGHALRIPSGFISYILNRHDNQNLRVAKISMPVNTPGQFEDFFPASSRDQSSYLQGFSRNTLEAAFNAEFNEIRRVLLEENAGGEQEERGQRRWSTRSSENNEGVIVKVSKEHVEELTKHAKSVSKKGSEEEGDITNPINLREGEPDLSNNFGKLFEVKPDKKNPQLQDLDMMLTCVEIKEGALMLPHFNSKAMVIVVVNKGTGNLELVAVRKEQQQRGRREEEEDEDEEEEGSNREVRRYTARLKEGDVFIMPAAHPVAINASSELHLLGFGINAENNHRIFLAGDKDNVIDQIEKQAKDLAFPGSGEQVEKLIKNQKESHFVSARPQSQSQSPSSPEKESPEKEDQEEENQGGKGPLLSILKAFN
UniProt: P43238 IUIS: Ara h 1Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
| 1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
|---|---|---|---|---|---|
| R | VSPLMLLLGILVLASVSATHAK | S | 0 | 0.444 | 0.12606 |
| K | TENPCAQR | C | 0 | 0.262 | 0.19602 |
| R | CLQSCQQEPDDLK | Q | 0 | 0.567 | 0.36178 |
| R | GHTGTTNQR | S | 0 | 0.331 | 0.1523 |
| R | QPGDYDDDR | R | 0 | 0.261 | 0.16496 |
| R | WGPAGPR | E | 0 | 0.262 | 0.22094 |
| R | RPSHQQPR | K | 0 | 0.182 | 0.19222 |
| R | EGEQEWGTPGSHVR | E | 1 | 0.608 | 0.39554 |
| R | NNPFYFPSR | R | 4 | 0.489 | 0.43444 |
| R | YGNQNGR | I | 0 | 0.25 | 0.11132 |
| R | QFQNLQNHR | I | 1 | 0.366 | 0.23524 |
| R | IVQIEAKPNTLVLPK | H | 1 | 0.433 | 0.7547 |
| K | HADADNILVIQQGQATVTVANGNNR | K | 0 | 0.669 | 0.31584 |
| K | SFNLDEGHALR | I | 4 | 0.713 | 0.56688 |
| R | IPSGFISYILNR | H | 0 | 0.638 | 0.3591 |
| R | HDNQNLR | V | 0 | 0.25 | 0.11876 |
| K | ISMPVNTPGQFEDFFPASSR | D | 1 | 0.911 | 0.17808 |
| R | DQSSYLQGFSR | N | 1 | 0.597 | 0.44536 |
| R | NTLEAAFNAEFNEIR | R | 3 | 0.7 | 0.47562 |
| R | VLLEENAGGEQEER | G | 6 | 0.618 | 0.70694 |
| R | SSENNEGVIVK | V | 1 | 0.504 | 0.62688 |
| K | EHVEELTK | H | 1 | 0.278 | 0.27542 |
| K | GSEEEGDITNPINLR | E | 0 | 0.729 | 0.82228 |
| R | EGEPDLSNNFGK | L | 1 | 0.549 | 0.33306 |
| K | LFEVKPDK | K | 0 | 0.251 | 0.56546 |
| K | NPQLQDLDMMLTCVEIK | E | 0 | 0.556 | 0.12114 |
| K | EGALMLPHFNSK | A | 1 | 0.544 | 0.54662 |
| K | AMVIVVVNK | G | 2 | 0.312 | 0.36754 |
| K | GTGNLELVAVR | K | 6 | 0.658 | 0.85124 |
| R | EEEEDEDEEEEGSNR | E | 1 | 0.39 | 0.2348 |
| R | IFLAGDK | D | 0 | 0.263 | 0.60074 |
| K | DNVIDQIEK | Q | 0 | 0.345 | 0.47952 |
| K | DLAFPGSGEQVEK | L | 6 | 0.65 | 0.92054 |
| K | ESHFVSARPQSQSQSPSSPEK | E | 0 | 0.289 | 0.3648 |
| K | EDQEEENQGGK | G | 0 | 0.248 | 0.16262 |
| K | GPLLSILK | A | 0 | 0.31 | 0.55638 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.