Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.
This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.
Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.
RQQPEENACQFQRLNAQRPDNRIESEGGYIETWNPNNQEFECAGVALSRLVLRRNALRRPFYSNAPQEIFIQQGRGYFGLIFPGCPRHYEEPHTQGRRSQSQRPPRRLQGEDQSQQQRDSHQKVHRFDEGDLIAVPTGVAFWLYNDHDTDVVAVSLTDTNNNDNQLDQFPRRFNLAGNTEQEFLRYQQQSRQSRRRSLPYSPYSPQSQPRQEEREFSPRGQHSRRERAGQEEENEGGNIFSGFTPEFLEQAFQVDDRQIVQNLRGETESEEEGAIVTVRGGLRILSPDRKRRADEEEEYDEDEYEYDEEDRRRGRGSRGRGNGIEETICTASAKKNIGRNRSPDIYNPQAGSLKTANDLNLLILRWLGPSAEYGNLYRNALFVAHYNTNAHSIIYRLRGRAHVQVVDSNGNRVYDEELQEGHVLVVPQNFAVAGKSQSENFEYVAFKTDSRPSIANLAGENSVIDNLPEEVVANSYGLQREQARQLKNNNPFKFFVPPSQQSPRAVA
UniProt: O82580 IUIS: Ara h 3Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.
1 | Peptide | 2 | Exp.3 | ESP4 | CONSeQ5 |
---|---|---|---|---|---|
R | QQPEENACQFQR | L | 2 | 0.43 | 0.38616 |
R | LNAQRPDNR | I | 3 | 0.239 | 0.1893 |
R | IESEGGYIETWNPNNQEFECAGVALSR | L | 0 | 0.386 | 0.10116 |
R | RPFYSNAPQEIFIQQGR | G | 7 | 0.352 | 0.34374 |
R | GYFGLIFPGCPR | H | 0 | 0.638 | 0.3769 |
R | HYEEPHTQGR | R | 0 | 0.365 | 0.14644 |
R | SQSQRPPR | R | 0 | 0.207 | 0.1644 |
R | LQGEDQSQQQR | D | 0 | 0.32 | 0.28052 |
R | FNLAGNTEQEFLR | Y | 0 | 0.736 | 0.58388 |
R | SLPYSPYSPQSQPR | Q | 0 | 0.685 | 0.38706 |
R | AGQEEENEGGNIFSGFTPEFLEQAFQVDDR | Q | 0 | 0.476 | 0.31282 |
R | QIVQNLR | G | 2 | 0.24 | 0.37028 |
R | GETESEEEGAIVTVR | G | 2 | 0.567 | 0.63084 |
R | ADEEEEYDEDEYEYDEEDR | R | 1 | 0.226 | 0.3006 |
R | GNGIEETICTASAK | K | 0 | 0.577 | 0.72198 |
R | SPDIYNPQAGSLK | T | 10 | 0.693 | 0.78552 |
K | TANDLNLLILR | W | 2 | 0.665 | 0.42998 |
R | WLGPSAEYGNLYR | N | 0 | 0.641 | 0.3896 |
R | NALFVAHYNTNAHSIIYR | L | 0 | 0.486 | 0.11108 |
R | AHVQVVDSNGNR | V | 3 | 0.674 | 0.39236 |
R | VYDEELQEGHVLVVPQNFAVAGK | S | 1 | 0.679 | 0.08226 |
K | SQSENFEYVAFK | T | 3 | 0.626 | 0.47618 |
K | FFVPPSQQSPR | A | 1 | 0.648 | 0.55052 |
K | LLELSFCFCFLVLGASSISFR | Q | 0 | 0.164 | 0.05036 |
R | QQPEENACQFQR | L | 2 | 0.43 | 0.38616 |
R | LNAQRPDNR | I | 3 | 0.239 | 0.1893 |
R | IESEGGYIETWNPNNQEFECAGVALSR | L | 0 | 0.386 | 0.10116 |
R | RPFYSNAPQEIFIQQGR | G | 7 | 0.352 | 0.34374 |
R | GYFGLIFPGCPSTYEEPAQQGR | R | 1 | 0.746 | 0.17966 |
R | YQSQRPPR | R | 0 | 0.227 | 0.2323 |
R | LQEEDQSQQQQDSHQK | V | 0 | 0.473 | 0.33526 |
R | FNLAGNHEQEFLR | Y | 6 | 0.679 | 0.38002 |
R | SLPYSPYSPHSRPR | R | 0 | 0.25 | 0.28026 |
R | AGQEEEDEGGNIFSGFTPEFLEQAFQVDDR | Q | 0 | 0.47 | 0.31752 |
R | QIVQNLWGENESEEEGAIVTVR | G | 1 | 0.429 | 0.11842 |
R | ILSPDGTR | G | 0 | 0.282 | 0.731 |
R | GADEEEEYDEDQYEYHEQDGR | R | 0 | 0.319 | 0.29374 |
R | GGGNGIEETICTACVK | K | 0 | 0.571 | 0.50222 |
R | SPHIYDPQR | W | 0 | 0.336 | 0.31046 |
R | WFTQNCHDLNLLILR | W | 0 | 0.435 | 0.0559 |
R | WLGLSAEYGNLYR | N | 3 | 0.527 | 0.2473 |
R | NALFVPHYNTNAHSIIYALR | G | 1 | 0.483 | 0.08724 |
R | AHVQVVDSNGNR | V | 3 | 0.674 | 0.39236 |
R | VYDEELQEGHVLVVPQNFAVAGK | S | 1 | 0.679 | 0.08226 |
K | SQSENFEYVAFK | T | 3 | 0.626 | 0.47618 |
K | FFVPPFQQSPR | A | 1 | 0.599 | 0.57298 |
1 Previous amino acid (^ = Start of protein)
2 Next amino acid ($ = End of protein)
3 Exp. = Number of publications in which this peptide has been reported experimentally
4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi
5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi
Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.
Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.